OpenSlide is a C library for reading whole slide image files. Prior to 4.0.1, a behavior change in libtiff 4.7.1 causes the indirect TIFF tile path in src/openslide-decode-tiff.c and _openslide_tiff_read_tile() to request a full-height destination for a partial bottom tile row, allowing uninitialized heap memory to enter pixel data returned by openslide_read_region(). A crafted but valid slide can trigger the issue in TIFF-based formats other than Hamamatsu NDPI when a network service renders attacker-provided slides. Successful extraction depends on pixel transparency handling and recompression, OpenSlide with libtiff 4.7.0 or earlier is not affected, and official binary builds 4.0.0.10 and 4.0.0.11 are affected. This issue is fixed in OpenSlide 4.0.1 and official binary build 4.0.0.12.
Advisories

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Fixes

Solution

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Workaround

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History

Fri, 18 Sep 2026 23:45:00 +0000

Type Values Removed Values Added
First Time appeared Openslide
Openslide openslide
Vendors & Products Openslide
Openslide openslide

Fri, 18 Sep 2026 21:30:00 +0000

Type Values Removed Values Added
Metrics ssvc

{'options': {'Automatable': 'no', 'Exploitation': 'none', 'Technical Impact': 'partial'}, 'version': '2.0.3'}


Thu, 17 Sep 2026 20:45:00 +0000

Type Values Removed Values Added
Description OpenSlide is a C library for reading whole slide image files. Prior to 4.0.1, a behavior change in libtiff 4.7.1 causes the indirect TIFF tile path in src/openslide-decode-tiff.c and _openslide_tiff_read_tile() to request a full-height destination for a partial bottom tile row, allowing uninitialized heap memory to enter pixel data returned by openslide_read_region(). A crafted but valid slide can trigger the issue in TIFF-based formats other than Hamamatsu NDPI when a network service renders attacker-provided slides. Successful extraction depends on pixel transparency handling and recompression, OpenSlide with libtiff 4.7.0 or earlier is not affected, and official binary builds 4.0.0.10 and 4.0.0.11 are affected. This issue is fixed in OpenSlide 4.0.1 and official binary build 4.0.0.12.
Title OpenSlide: openslide_read_region() returns uninitialized memory with libtiff 4.7.1
Weaknesses CWE-758
CWE-908
References
Metrics cvssV4_0

{'score': 5.3, 'vector': 'CVSS:4.0/AV:N/AC:L/AT:N/PR:L/UI:N/VC:L/VI:N/VA:N/SC:N/SI:N/SA:N'}


Projects

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cve-icon MITRE

Status: PUBLISHED

Assigner: GitHub_M

Published:

Updated: 2026-09-18T20:06:41.600Z

Reserved: 2026-06-15T19:45:23.540Z

Link: CVE-2026-54604

cve-icon Vulnrichment

Updated: 2026-09-18T20:06:37.749Z

cve-icon NVD

Status : Received

Published: 2026-09-17T21:17:17.000

Modified: 2026-09-18T20:17:16.747

Link: CVE-2026-54604

cve-icon Redhat

No data.

cve-icon OpenCVE Enrichment

Updated: 2026-09-19T01:30:17Z

Weaknesses